High-dimensional phenotypic mapping of human dendritic cells reveals interindividual variation and tissue specialization.
Alcántara-Hernández M*, Leylek R*, Wagar LE, Engleman EG, Keler T, Marinkovich MP, Davis MM, Nolan GP, Idoyaga J. Immunity. (2017)
*These authors contributed equally to this work.


Expansion and activation of CD103+ dendritic cell progenitors at the tumor site enhances tumor responses to therapeutic PD-L1 and BRAF inhibition.
Salmon H, Idoyaga J, Rahman A, Lebboeuf M, Remark R, Jordan S, Casanova-Acebes M, Khudoynazarova M, Agudo J, Tung N, Chakarov S, Rivera C, Hogstad B, Bosenberg M, Hashimoto D, Gnjatic S, Bhardwaj N, Palucka AK, Brown BD, Brody J, Ginhoux F, Merad M. Immunity. (2016)


CDKN1A regulates Langerhans cell survival and promotes Treg cell generation upon exposure to ionizing irradiation.
Price, JG*, Idoyaga J*, Salmon H, Hogstad B, Bigarella CL, Ghaffari S, Leboeuf M, Merad M. Nature Immunol. (2015)
*These authors contributed equally to this work.


Murine langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross tolerance.
Flacher V, Tripp CH, Mairhofer DG, Steinman RM, Stoitzner P, Idoyaga J, Romani N. EMBO Mol Med. (2014)


Specialized role of migratory dendritic cells in peripheral tolerance induction.
Idoyaga J, Fiorese C, Zbytnuik L, Lubkin A, Miller J, Malissen B, Mucida D, Merad M, Steinman RM. J Clin Invest. (2013)


Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells.
Barbuto S*, Idoyaga J*, Vila-Perelló M, Longhi MP, Breton G, Steinman RM, Muir TW. Nat Chem Biol. (2013)
*These authors contributed equally to this work.


Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity.
Matos I, Mizenina O, Lubkin A, Steinman RM, Idoyaga J. PLoS One. (2013)


Treml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 protein.
Hemmi H, Zaidi N, Wang B, Matos I, Fiorese C, Lubkin A, Zbytnuik L, Suda K, Zhang K, Noda M, Kaisho T, Steinman RM, Idoyaga J. J Immunol. (2012)


Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity.
Trumpfheller C, Longhi MP, Caskey M, Idoyaga J, Bozzacco L, Keler T, Schlesinger SJ, Steinman RM. J Intern Med. (2012)


Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.
Idoyaga J, Lubkin A, Fiorese C, Lahoud MH, Caminschi I, Huang Y, Rodriguez A, Clausen BE, Park CG, Trumpfheller C, Steinman RM. Proc Natl Acad Sci USA. (2011)


Features of the dendritic cell lineage.
Steinman RM, Idoyaga J. Immunol Rev. (2010)


Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis.
Flacher V, Tripp CH, Stoitzner P, Haid B, Ebner S, Del Frari B, Koch F, Park CG, Steinman RM, Idoyaga J, Romani N. J Invest Dermatol. (2010)


Antibody to Langerin/CD207 localizes large numbers of CD8alpha+ dendritic cells to the marginal zone of mouse spleen.
Idoyaga J, Suda N, Suda K, Park CG, Steinman RM. Proc Natl Acad Sci USA. (2009)


Cutting edge: langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo.
Idoyaga J, Cheong C, Suda K, Suda N, Kim JY, Lee H, Park CG, Steinman RM. J Immunol. (2008)